The CRISPR technology was first used in the United States for the treatment of cancer patients

In 2016 the National institutes of health allowed the research team from the University of Pennsylvania (UPenn) to begin testing the technology CRISPR (editing of the genome) in humans. However, controversial and has earned a very mixed assessment scientists, the technology only now reached clinical trials in the United States. Representatives of the University UPenn in an interview with NPR confirmed that officially began its use. Scientists note that this event may lead to wider use of technology in the future.

The CRISPR technology, scientists UPenn used for the treatment of two cancer patients at a late stage of the disease. One of them observed multiple foci of melanoma, the other is suffering from sarcoma. It is noted that patients who are not helped all available means of treatment, volunteered to go through the editing program of genes CRISPR.

First, the researchers extracted immune system cells from patients, using СRISPR for editing cells “programmed” them to fight the tumor, and then returned them to the organisms of patients. The results of this study will soon be presented at a medical Congress and will also receive publication.

Traditional gene therapy uses viruses to insert new genes into cells to treat diseases. The CRISPR technology in turn allows you to largely avoid the use of viruses, reducing the risk of infection. Directly instead, scientists make changes in DNA, using special molecular tools.

Researchers from UPenn, believe their work is completely different from what made Chinese scientist Hae Cisangkuy. Last used CRISPR to edit genes in human embryos, thereby starting the chain of transmission of genetic modifications to future generations. However, he undertook this work alone, never saying. In conditions when the entire scientific community, was still the question of the safety of AUSTRALIAN people. In the end, this event led to a wave of protests and demands for a moratorium on editing the genes of hereditary traits. Research professionals from UPenn, meanwhile, focused on medical treatment with the modification of the DNA of adults who have not responded none of the existing methods of treatment.

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